Under normal circumstances, yes. But there are exceptions. Do you use your computer as a media server with Plex or something similar? Then leaving it on allows you to watch your shows remotely, thanks to the digital age. Is it tied into your home somehow, perhaps monitoring your smart devices? You can probably access your smart devices via a phone app, but you may want to let the computer stay on to allow for logging of what’s going on.
In short, if it’s just for surfing the net and reading email, shut it off. If it’s working behind the scenes, leave it on.